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Magnet-based drug delivery system shows promise for cancer treatment

A team of researchers at the University of Georgia has developed a non-invasive method of delivering drugs directly to cancerous tissue using magnetic forces, a form of treatment that could significantly reduce the toxic side effects of chemotherapy. “We showed that we can deliver anti-cancer drugs exactly in the area …

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Boosting Sirt4 gene activity extends healthy lifespan in fruit flies

A new study on the mechanics of aging and longevity finds that fruit flies inhibited from producing the protein Sirt4 — which is also found in humans — are short-lived, while flies modified to make extra Sirt4 are long-lived. In addition, flies lacking Sirt4 display increased sensitivity to starvation, decreased fertility …

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Cells protect genes more than rest of genome

Whilst DNA sequence mutation is the fundamental fuel of species evolution, mutations in genes are often harmful. As a form of defence, organisms have evolved repair mechanisms to correct the DNA sequence following mutation. One of these mechanisms, is termed DNA mismatch repair (MMR). It corrects mutations that arise during …

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Cancer targeted with reusable ‘stinging nettle’ treatment

Cancer cells can be destroyed more effectively and selectively with a unique new reusable treatment, activated with a substance found in stinging nettles and ants – thanks to new research by the University of Warwick. Dr James Coverdale (L) and Dr Isolda Romero-Canelón (R) working in the laboratory – credit …

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PupilScreen aims to allow parents, coaches, medics to detect concussion, brain injuries with a smartphone

University of Washington researchers are developing the first smartphone app that is capable of objectively detecting concussion and other traumatic brain injuries in the field: on the sidelines of a sports game, on a battlefield or in the home of an elderly person prone to falls. PupilScreen aims to allow …

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How the brain keeps time

Timing is critical for playing a musical instrument, swinging a baseball bat, and many other activities. Neuroscientists have come up with several models of how the brain achieves its exquisite control over timing, the most prominent being that there is a centralized clock, or pacemaker, somewhere in the brain that …

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Smart Underwear Prevents Back Stress

Professor Karl Zelik with Ph.D student Erik Lamers from Vanderbilt University created a mechanized undergarment, that could prevent back stress. It is a lightweight two-part suit is made up of nylon canvas, Lycra and polyester. Two straps go down from the top section and across the back, joining up with natural …

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Liquid Biopsy May Be New Way to Detect Liver Cancer Earlier, Easier

An international team of researchers at University of California San Diego School of Medicine and Moores Cancer Center, with colleagues at Sun Yet-sun University Cancer Center and other collaborating institutions, have developed a new diagnostic and prognosis method for early detection of hepatocellular carcinoma (HCC), based on a simple blood …

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DNA Mutations Shed in Blood Predicts Response to Immunotherapy in Patients with Cancer

In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies. “We can help predict response to immunotherapy by measuring the number of mutations in circulating tumor DNA using a …

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Microscope can scan tumors during surgery and examine cancer biopsies in 3-D

When women undergo lumpectomies to remove breast cancer, doctors try to remove all the cancerous tissue while conserving as much of the healthy breast tissue as possible. But currently there’s no reliable way to determine during surgery whether the excised tissue is completely cancer-free at its margins — the proof …

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