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Magnet-based drug delivery system shows promise for cancer treatment

A team of researchers at the University of Georgia has developed a non-invasive method of delivering drugs directly to cancerous tissue using magnetic forces, a form of treatment that could significantly reduce the toxic side effects of chemotherapy. “We showed that we can deliver anti-cancer drugs exactly in the area …

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Boosting Sirt4 gene activity extends healthy lifespan in fruit flies

A new study on the mechanics of aging and longevity finds that fruit flies inhibited from producing the protein Sirt4 — which is also found in humans — are short-lived, while flies modified to make extra Sirt4 are long-lived. In addition, flies lacking Sirt4 display increased sensitivity to starvation, decreased fertility …

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Cells protect genes more than rest of genome

Whilst DNA sequence mutation is the fundamental fuel of species evolution, mutations in genes are often harmful. As a form of defence, organisms have evolved repair mechanisms to correct the DNA sequence following mutation. One of these mechanisms, is termed DNA mismatch repair (MMR). It corrects mutations that arise during …

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Cancer targeted with reusable ‘stinging nettle’ treatment

Cancer cells can be destroyed more effectively and selectively with a unique new reusable treatment, activated with a substance found in stinging nettles and ants – thanks to new research by the University of Warwick. Dr James Coverdale (L) and Dr Isolda Romero-Canelón (R) working in the laboratory – credit …

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Mapping Earth’s Microbiome | Technology Org

More than 27,500 samples collected across seven continents and 43 countries. More than 307,500 unique DNA sequences. One reference map of the bacteria and related microbes that call Planet Earth home. This is the result of the Earth Microbiome Project, an effort by an extensive global team co-led by researchers at …

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DNA Mutations Shed in Blood Predicts Response to Immunotherapy in Patients with Cancer

In a first-of-its-kind study, University of California San Diego School of Medicine researchers report that a blood sample, or liquid biopsy, can reveal which patients will respond to checkpoint inhibitor-based immunotherapies. “We can help predict response to immunotherapy by measuring the number of mutations in circulating tumor DNA using a …

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Microscope can scan tumors during surgery and examine cancer biopsies in 3-D

When women undergo lumpectomies to remove breast cancer, doctors try to remove all the cancerous tissue while conserving as much of the healthy breast tissue as possible. But currently there’s no reliable way to determine during surgery whether the excised tissue is completely cancer-free at its margins — the proof …

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NIST’s Quick Test May Speed Antibiotic Treatment and Combat Drug Resistance

Researchers at the National Institute of Standards and Technology (NIST) have demonstrated a potential new tactic for rapidly determining whether an antibiotic combats a given infection, thus hastening effective medical treatment and limiting the development of drug-resistant bacteria. Their method can quickly sense mechanical fluctuations of bacterial cells and any changes induced by an …

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Chemists Create the Ultimate Natural Sunscreen

Chemists, materials scientists and nanoengineers at UC San Diego have created what may be the ultimate natural sunscreen. In a paper published in the American Chemical Society journal ACS Central Science, they report the development of nanoparticles that mimic the behavior of natural melanosomes, melanin-producing cell structures that protect our …

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New microscope technique reveals internal structure of live embryos

University of Illinois researchers have developed a way to produce 3-D images of live embryos in cattle that could help determine embryo viability before in vitro fertilization in humans. Infertility can be devastating for those who want children. Many seek treatment, and the cost of a single IVF cycle can …

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